Knockout of tau causes mild deficits in neurite growth and AIS formation but does not alter neuronal activity. Credit: Alzheimer’s & Dementia (2025). DOI: 10.1002/alz.14403, https://alz-journals.onlinelibrary.wiley.com/doi/full/10.1002/alz.14403 A research team at
Brain cells (green) derived from people with Alzheimer’s disease (center) show far fewer projections than healthy neurons (left). Blocking S-nitrosylation of CRTC1, however, restores the cells to a healthier state
Neuronal marker induction by dbcAMP or forskolin. Credit: Proceedings of the National Academy of Sciences (2025). DOI: 10.1073/pnas.2415557122 UCLA scientists have identified a potential new strategy for treating glioblastoma, the
Investigation of synaptic properties in control- and patient-derived neuronal cultures. Credit: Nature Communications (2025). DOI: 10.1038/s41467-025-56998-1 When neurons do not migrate to their proper place during brain development, it causes
by D’Or Institute for Research and Education Saxitoxin blocks spontaneous activity in hiPSC-derived neuronal cultures. Credit: Scientific Reports (2024). DOI: 10.1038/s41598-024-73873-z In recent years, the Zika virus (ZIKV) epidemic that
Differences in neuronal activation in mice with intact Tregs (left) and depleted Tregs (right). The finding demonstrates that Tregs play a role in ensuring healthy neuronal activity under normal conditions.