by Rimma Gerenstein , Albert-Ludwigs-Universität Freiburg im Breisgau Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-53217-1 In healthy rodent brains, newborn neurons are constantly generated in the stem cell niche, known as
Credit: Cell Stem Cell (2024). DOI: 10.1016/j.stem.2024.09.013 When a neuron ages, it loses synaptic connections with other neurons, it is less able to transmit nerve impulses, and its metabolism is
A cerebral organoid showing rosettes (or whirls) of newly developing and migrating new neurons (shown in purplish-red). Credit: Scripps Research Using stem cells generated from patients with a rare and
Image of a single quiescent neural stem cell with its hallmark cellular protrusion extending from the cell body from Drosophila larval brains six hours after larval hatching, with the membrane
Credit: CC0 Public Domain Most neurons in the human brain last a lifetime, and for good reason. Intricate, long-term information is preserved in the complex structural relationships between their synapses.
Alysson R. Muotri, Ph.D., University of California, San Diego, U.S. Credit: Brain Medicine (2024). https://doi.org/10.61373/bm024k.0082 In an interview published in Brain Medicine, Dr. Alysson Muotri—Professor in the Department of Pediatrics