Huntington’s Disease organoids (right) exhibit almost no neural progenitors (red) and also show defects in cellular polarity (yelllow). These defects have been described in the literature in human fetuses with
by Institute for the Advanced Study of Human Biology (ASHBi), Kyoto University Human brain organoids are three-dimensional neural tissues derived from stem cells that can mimic some aspects of the
In the Drosophila brain, dormant neural stem cells with protrusions rich in actin filaments. Credit: Duke-NUS Medical School Scientists from Duke-NUS Medical School and the Mechanobiology Institute (MBI) at the
Working model of the termination of medulla NBs. Credit: eLife (2024). DOI: 10.7554/eLife.96876 Peter Mac researchers have discovered new insights into neural stem cell development in fruit flies that may
Credit: CC0 Public Domain When Ralda Nehme, a cell biologist and neuroscientist, first started her lab at the Stanley Center for Psychiatric Research at the Broad Institute of MIT and
by Ingrid Fadelli , Medical Xpress Analysis of the developmental cell atlas. a, Workflow to obtain single-cell RNA (scRNA) expression and CUT&Tag data for three histone modifications (H3K27me3, H3K4me3 and